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Creators/Authors contains: "Pfister, Hanspeter"

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  1. Free, publicly-accessible full text available January 1, 2026
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  4. System-prompting is a standard tool for customizing language-model chatbots, enabling them to follow a specific instruction. An implicit assumption in the use of system prompts is that they will be stable, so the chatbot will continue to generate text according to the stipulated instructions for the duration of a conversation. We propose a quantitative benchmark to test this assumption, evaluating instruction stability via self-chats between two instructed chatbots. Testing popular models like LLaMA2-chat-70B and GPT-3.5, we reveal a significant instruction drift within eight rounds of conversations. An empirical and theoretical analysis of this phenomenon suggests the transformer attention mechanism plays a role, due to attention decay over long exchanges. To combat attention decay and instruction drift, we propose a lightweight method called split-softmax, which compares favorably against two strong baselines. 
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  5. Gaze-annotated facial data is crucial for training deep neural networks (DNNs) for gaze estimation. However, obtaining these data is labor-intensive and requires specialized equipment due to the challenge of accurately annotating the gaze direction of a subject. In this work, we present a generative framework to create annotated gaze data by leveraging the benefits of labeled and unlabeled data sources. We propose a Gaze-aware Compositional GAN that learns to generate annotated facial images from a limited labeled dataset. Then we transfer this model to an unlabeled data domain to take advantage of the diversity it provides. Experiments demonstrate our approach's effectiveness in generating within-domain image augmentations in the ETH-XGaze dataset and cross-domain augmentations in the CelebAMask-HQ dataset domain for gaze estimation DNN training. We also show additional applications of our work, which include facial image editing and gaze redirection. 
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  6. Mapping neuronal networks is a central focus in neuroscience. While volume electron microscopy (vEM) can reveal the fine structure of neuronal networks (connectomics), it does not provide molecular information to identify cell types or functions. We developed an approach that uses fluorescent single-chain variable fragments (scFvs) to perform multiplexed detergent-free immunolabeling and volumetric-correlated-light-and-electron-microscopy on the same sample. We generated eight fluorescent scFvs targeting brain markers. Six fluorescent probes were imaged in the cerebellum of a female mouse, using confocal microscopy with spectral unmixing, followed by vEM of the same sample. The results provide excellent ultrastructure superimposed with multiple fluorescence channels. Using this approach, we documented a poorly described cell type, two types of mossy fiber terminals, and the subcellular localization of one type of ion channel. Because scFvs can be derived from existing monoclonal antibodies, hundreds of such probes can be generated to enable molecular overlays for connectomic studies. 
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    Free, publicly-accessible full text available December 1, 2025
  7. Trust is an essential aspect of data visualization, as it plays a crucial role in the interpretation and decision-making processes of users. While research in social sciences outlines the multi-dimensional factors that can play a role in trust formation, most data visualization trust researchers employ a single-item scale to measure trust. We address this gap by proposing a comprehensive, multidimensional conceptualization and operationalization of trust in visualization. We do this by applying general theories of trust from social sciences, as well as synthesizing and extending earlier work and factors identified by studies in the visualization field. We apply a two-dimensional approach to trust in visualization, to distinguish between cognitive and affective elements, as well as between visualization and data-specific trust antecedents. We use our framework to design and run a large crowd-sourced study to quantify the role of visual complexity in establishing trust in science visualizations. Our study provides empirical evidence for several aspects of our proposed theoretical framework, most notably the impact of cognition, affective responses, and individual differences when establishing trust in visualizations. 
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